Join me in continuing fighting the good fight
In 2017 I completed a 12 marathon in 12 month challenge, to raise awareness for Aortic Dissection (AD) and money to directly fund an AD surgical masterclass for heart surgeons. This year I’m running the New York City Marathon in November to focus our efforts on supporting the great research by the John Ritter Foundation (JFR) into the genes causing AD, to continue raising awareness and of course pursue the legacy and the reason why I’m doing this in the first place, for Tim Fleming.
As in Tim’s case, the mortality rate is high among those who suffer acute aortic dissection. Lives can be saved by timely diagnosis of AD and proper treatment to prevent the medical emergency created by AD. In any family where AD is present, there is a 50% chance that the genes predisposed to the condition are passed to the next generation and it is here where the money I raise will be focused.
Through the groundbreaking research of the JRF 14 genes have been identified that lead to heritable aortic disease. However, 70% of families that have a history of aortic disease do not have the abnormalities in these genes identifies to date. JRF are pioneering this research and earlier this year (American Journal of Human Genetics, April 2018) identified a previously unidentified gene that leads to AD. However, more needs to be done to identify the remaining affected genes and give a better chance to these families affected.
Studies have projected that the number of those carrying one of these genes and therefore prone to AD will double in the next 40 years. During this time, a condition that traditionally is more prominent in men will shift with more type-A dissection events occurring in women and overall an equal sex-ratio between type A and B. The time is now to boost research and reduce these number of people losing their lives to the treatable disease.
Join me in continuing to fight the good fight - Every penny we raise will go directly to JRF.
Please support me now and give as generously as you can. Together we can make the difference and save the lives of so many!