A Legacy of Leadership The Lupus Research Alliance was created by the merger of three leaders in lupus research – the Alliance for Lupus Research, the Lupus Research Institute and the S.L.E. Lupus Foundation – united in the quest to free the world of this autoimmune disease through the power of science. We are the world’s largest and most powerful private funder of innovative lupus research and serve as the primary catalyst setting the agenda to drive new scientific discoveries into prevention, treatment and cure of the disease. Collectively, the three legacy organizations have devoted more than 75 years to the cause and are responsible for funding over $200 million to support lupus research programs. The Board of Directors promises to cover all administrative and operating costs of the organization, ensuring that 100% of all donations go directly to funding research programs in order to realize our vision of a world free of lupus. About Lupus Lupus is a chronic, complex autoimmune disease that affects millions of people worldwide. More than 90% of people diagnosed with lupus are women, mostly young women between the ages of 15 to 44. Women of color are especially at risk. In lupus, the immune system, which is designed to protect against infection, creates antibodies that attack the body’s own tissues and organs – including the kidneys, brain, heart, lungs, blood, skin, and joints.