English Setter Fanciers vs Epilepsy
Organized by: English Setters Fanciers Unite
English Setter Fanciers are calling for everyone around the World who agree that DNA markers are the key to trying to eliminate or at best curtail epilepsy in the breed to donate to this fundraiser to send funds for further research to the University of Missouri who have been working tirelessly to find markers in many breeds, to now, also focus on English Setters. The initial plan would be to do Whole Genome Sequences on 1-3 epileptic English Setters. The cost of WGS has just come down, and now is $2500 per dog (half what it was just a few weeks ago!). Ideally, we’d like to do 2 or 3 affected dogs, and then mine the resulting data for possible epilepsy mutations. If we’re very lucky, maybe something obvious will appear in that analysis – but most likely epilepsy is going to be complex, and we will be looking at multiple risk factors combining to push an individual past a threshold, resulting in seizures. The second phase would be making multiplexed panels of possible epilepsy mutations, and screening hundreds or thousands of dogs. With new technology coming available to the University of Missouri, at the cost of $180,000 in the next few months, they will be able to screen many dogs for many mutations very efficiently. This phase of the project is anticipated to be launched in about a year, at a cost of about $10,000 per breed included. Funds are needed for ongoing research and it is our hope that we can depend on all of the English Setter Fanciers around the World. Please help.......donate!